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DNA Nanotechnology

DNA Nanotechnology

Research

DNA Nanotechnology

  • AI-Driven DNA/RNA Nanostructure Design

  • Dynamic DNA Origami & Molecular Machines

  • Programmable Nucleic Acid Therapeutics (mRNA/CRISPR Delivery)

  • Hierarchical Self-assembly for Smart Materials

  • AI 기반 DNA/RNA 나노구조 설계

  • 동적 DNA 오리가미 및 분자 기계 (Molecular Machines)

  • 프로그래밍 가능한 핵산 치료제 (mRNA/CRISPR 전달 시스템)

  • 스마트 소재를 위한 계층적 자기조립

  • No. 5

    Computer-aided design software and simulation tools for DNA nanoparticles

    Trinh, M.C., Jun, H.†

    Advanced Materials Technologies, 11(4):e00438

    2026. 02. 19

    IF 6.2

    Article

    Computer-aided design software and simulation tools for DNA nanoparticles

    Classification of DNA Nanoparticle CAD Software

    This review chronologically examines computer-aided design (CAD) software designed to overcome limitations of manual design. It categorizes design methodologies into bottom-up and top-down strategies, encompassing tile-based and frame-based architectures.

    Simulation Methodologies and Future Prospects

    The study classifies simulation tools into finite-element and coarse-grained molecular dynamics models. It highlights future needs, including unified automation platforms and deep learning integration to conserve time and effort.

  • No. 4

    Programming 2D Supramolecular Assemblies with Wireframe DNA Origami

    Wang, X., Jun, H., Bathe

    Journal of the American Chemical Society, 144: 4403-9

    2022. 03. 16

    IF 16.383, JCR 8.659%

    Article

    Programming 2D Supramolecular Assemblies with Wireframe DNA Origami

  • No. 3

    Automated sequence design of 2D wireframe DNA origami with honeycomb edges

    Jun, H.*, Wang, X., Bricker, W., Bathe, M.

    Nature Communications, 10: 5419

    2019. 11. 16

    IF 17.694, JCR 7.432%

    Article

  • No. 2

    Automated sequence design of 3D polyhedral wireframe DNA origami with honeycomb edges

    Jun, H.*, Shepherd, T., Zhang, K., Bricker, W., Li, S., Chiu W., Bathe, M.

    ACS Nano, 13: 2083-93

    2019. 01. 16

    IF 18.027, JCR 5.652%

    Article

  • No. 1

    Autonomously designed free-form 2D DNA origami

    Jun, H.*, Zhang, F., Ratanalert, S., Shepherd, T., Qi, X., Yan, H., Bathe, M.

    Science Advances, 5: eaav0655

    2019. 01. 16

    IF 14.980, JCR 8.784%

    Article

한국연구재단 우수신진연구 유전자 치료를 위한 하이브리드 RNA-DNA 오리가미 나노플랫폼 개발 2024-04-01 ~ 2029-03-31
한국연구재단 지역대학우수과학자 DNA 나노구조물의 물리-화학적 성질 예측을 위한 가상시스템 개발 2020-06-01 ~ 2024-05-31